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  1. Content type: Original research article

    Patients with acute kidney injury (AKI) requiring renal replacement therapy (RRT) have an increased short-term and long-term risk of mortality. In most North American intensive care units (ICUs), these patient...

    Authors: Bhanu Prasad, Michelle Urbanski, Thomas W. Ferguson, Erwin Karreman and Nav Tangri

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:36

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  2. Content type: Original research article

    Health behaviour change is an important component of management for patients with chronic kidney disease (CKD); however, the optimal method to promote health behaviour change for self-management of CKD is unkn...

    Authors: Lauren Galbraith, Brenda Hemmelgarn, Braden Manns, Susan Samuel, Joanne Kappel, Nadine Valk and Paul Ronksley

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:35

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  3. Content type: Review

    Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory disorder affecting nearly all organs, including the kidney. Tubulointerstitial nephritis (IgG4-TIN) is the most common form of IgG4-r...

    Authors: Shawna Mann, Michael A. Seidman, Sean J. Barbour, Adeera Levin, Mollie Carruthers and Luke Y. C. Chen

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:34

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  4. Content type: Original research article

    Current guidelines favor fistulas over catheters as vascular access. Yet, the observational literature comparing fistulas to catheters has important limitations and biases that may be difficult to overcome in ...

    Authors: Krishna Poinen, Matthew J. Oliver, Pietro Ravani, Sabine N. Van der Veer, Kitty J. Jager, Wim Van Biesen, Kevan R. Polkinghorne, Aviva Rosenfeld, Adriane M. Lewin, Mandeep Dulai and Robert R. Quinn

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:33

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  5. Content type: Original research article

    Significant practice variation exists in Canada with respect to timing of dialysis initiation in children. In the absence of evidence to guide practice, physicians’ perceptions may significantly influence deci...

    Authors: Jeremy A. Saban, Michael Zappitelli, Susan M. Samuel, Manish M. Sood, R. Todd Alexander, Steven Arora, Robin L. Erickson, Kristine Kroeker, Braden J. Manns and Allison B. Dart

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:31

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  6. Content type: Methodology

    A critical feature of any continuing medical education (CME) program is the inclusion of a needs assessment for its target audience. This assessment must identify both perceived and unperceived needs, so as to...

    Authors: Barry A. Cohen, Mark J. Courtney, Louise M. Moist and James Barton

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:30

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  7. Content type: Study protocol

    Despite many advantages over facility-based therapies, less than 25 % of prevalent dialysis patients in Ontario are on a home therapy. Interactive health communication applications, web-based packages for pati...

    Authors: Andrea Harvey, Michael Walsh, Arsh K. Jain, Eric Bosch, Cathy Moreau, Jocelyn Garland and K. Scott Brimble

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:29

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  8. Content type: Original research article

    Reactivation of latent Mycobacterium tuberculosis infection (LTBI) is a health concern for patients on dialysis or receiving a kidney transplant, as these patients are often immunosuppressed. The most frequently ...

    Authors: Rukhsana Foster, Thomas W. Ferguson, Claudio Rigatto, Blake Lerner, Navdeep Tangri and Paul Komenda

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:28

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  9. Content type: Original research article

    Compared with the general population, end-stage renal disease patients are at increased risk for bone loss and fractures. Nocturnal hemodialysis offers superior calcium-phosphate control and improved uremic cl...

    Authors: Bourne L. Auguste, Darren Yuen and Christopher T. Chan

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:27

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  10. Content type: Review

    To summarize a jointly held symposium by the Canadian Society of Nephrology (CSN), the Canadian Association of Nephrology Administrators (CANA), and the Canadian Kidney Knowledge Translation and Generation Net...

    Authors: David Collister, Randall Russell, Josee Verdon, Monica Beaulieu and Adeera Levin

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:32

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  11. Content type: Original research article

    Growth of the elderly population is linked to the increase of comorbid conditions such as chronic kidney disease (CKD), depression, and cognitive impairment (CI). Cognitive impairment can vary from minimal def...

    Authors: Carlos Edgardo Rodríguez-Angarita, Rafael Mauricio Sanabria-Arenas, Juan Diego Vargas–Jaramillo and Izcay Ronderos–Botero

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:26

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  12. Content type: Review

    Patients with end-stage renal disease (ESRD) are at a high risk of bacterial infection. We reviewed publications on risk factors, prevention, and treatment paradigms, as well as outcomes associated with bacter...

    Authors: Chris Lata, Louis Girard, Michael Parkins and Matthew T. James

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:24

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  13. Content type: Original research article

    Studies have shown that erythropoietin-stimulating agents (ESAs) protect mice against the development of diabetes through direct effects on pancreatic ß cells. However, the effect of ESAs on the incidence of d...

    Authors: Tess Montada-Atin, Diana Choi, Minna Woo, Ravi Retnakaran, Michael Huang, G. V. Ramesh Prasad and Jeffrey S. Zaltzman

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:23

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  14. Content type: Original research article

    Regional citrate hemodialysis anticoagulation is used when heparin is contraindicated, but most protocols require large infusions of calcium and frequent intradialytic plasma ionized calcium measurements.

    Authors: Richard F. Singer, Oliver Williams, Chari Mercado, Bonny Chen, Girish Talaulikar, Giles Walters and Darren M. Roberts

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:22

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  15. Content type: Original research article

    A number of case reports have suggested a possible association between atypical antipsychotic medications and hyponatremia. Currently, there are no reliable estimates of hyponatremia risk from atypical antipsy...

    Authors: Sonja Gandhi, Eric McArthur, Jeffrey P. Reiss, Muhammad M. Mamdani, Daniel G. Hackam, Matthew A. Weir and Amit X. Garg

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:21

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  16. Content type: Original research article

    Validation studies of acute kidney injury (AKI) diagnostic codes performed in the general population have shown poor sensitivity, but the accuracy of such codes in the kidney transplant population remains unkn...

    Authors: Amber O. Molnar, Carl van Walraven, Eric McArthur, Dean Fergusson, Amit X. Garg and Greg Knoll

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:18

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  17. Content type: Study protocol

    Guideline committees have identified the need for research to inform the provision of conservative care for older adults with stage 5 chronic kidney disease (CKD) who have a high burden of comorbidity or funct...

    Authors: Helen Tam-Tham, Brenda Hemmelgarn, David Campbell, Chandra Thomas, Robert Quinn, Karen Fruetel and Kathryn King-Shier

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:17

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  18. Content type: Original research article

    In end-stage renal disease (ESRD) patients, increased arterial stiffness detected by carotid-femoral pulse wave velocity (cf-PWV) is associated with fatal cardiovascular events and all-cause mortality. Since c...

    Authors: Rosendo A. Rodriguez, Valerie Cronin, Timothy Ramsay, Deborah Zimmerman, Marcel Ruzicka and Kevin D. Burns

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:20

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  19. Content type: Original research article

    Although the outcomes of transplantation with expanded criteria donor (ECD) kidneys are inferior to non-ECD transplants in the USA, the impact of the ECD classification on Canadian kidney transplant recipients...

    Authors: Ann Young, Stephanie N. Dixon, Greg A. Knoll, Amit X. Garg, Charmaine E. Lok, Ngan N. Lam and S. Joseph Kim

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:15

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  20. Content type: Original research article

    Studies in the USA report differences in opinion among parents of different ethnic groups toward genetic testing for their child; however, there are no studies that address this issue in the diverse ethnic and...

    Authors: Karlota Borges, Jovanka Vasilevska-Ristovska, Neesha Hussain-Shamsy, Viral Patel, Tonny Banh, Diane Hebert, Rachel J. Pearl, Seetha Radhakrishnan, Tino D. Piscione, Christoph P. B. Licht, Valerie Langlois, Leo Levin, Lisa Strug and Rulan S. Parekh

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:16

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  21. Content type: Review

    Acute kidney injury (AKI) is independently associated with the development of chronic kidney disease, endstage kidney disease and increased all-cause and cardiovascular-specific mortality. The severity of the ...

    Authors: Ravindra Mehta, Azra Bihorac, Nicholas M. Selby, Hude Quan, Stuart L. Goldstein, John A. Kellum, Claudio Ronco and Sean M. Bagshaw

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:13

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  22. Content type: Review

    Among hospitalized patients, acute kidney injury is common and associated with significant morbidity and risk for mortality. The use of electronic health records (EHR) for prediction and detection of this impo...

    Authors: Eric A. J. Hoste, Kianoush Kashani, Noel Gibney, F. Perry Wilson, Claudio Ronco, Stuart L. Goldstein, John A. Kellum and Sean M. Bagshaw

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:10

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  23. Content type: Review

    The data contained within the electronic health record (EHR) is “big” from the standpoint of volume, velocity, and variety. These circumstances and the pervasive trend towards EHR adoption have sparked interes...

    Authors: Scott M. Sutherland, Lakhmir S. Chawla, Sandra L. Kane-Gill, Raymond K. Hsu, Andrew A. Kramer, Stuart L. Goldstein, John A. Kellum, Claudio Ronco and Sean M. Bagshaw

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:11

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  24. Content type: Review

    Electronic medical records and clinical information systems are increasingly used in hospitals and can be leveraged to improve recognition and care for acute kidney injury. This Acute Dialysis Quality Initiati...

    Authors: Matthew T. James, Charles E. Hobson, Michael Darmon, Sumit Mohan, Darren Hudson, Stuart L. Goldstein, Claudio Ronco, John A. Kellum and Sean M. Bagshaw

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:9

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  25. Content type: Review

    The purpose of this review is to report how administrative data have been used to study AKI, identify current limitations, and suggest how these data sources might be enhanced to address knowledge gaps in the ...

    Authors: Edward D. Siew, Rajit K. Basu, Hannah Wunsch, Andrew D. Shaw, Stuart L Goldstein, Claudio Ronco, John A. Kellum and Sean M. Bagshaw

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:12

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  26. Content type: Editorial

    The world is immersed in “big data”. Big data has brought about radical innovations in the methods used to capture, transfer, store and analyze the vast quantities of data generated every minute of every day. At ...

    Authors: Sean M. Bagshaw, Stuart L. Goldstein, Claudio Ronco and John A. Kellum

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:5

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  27. Content type: Case report

    Pregnancy in patients on chronic hemodialysis therapy, though unlikely, does happen rarely. Intensive hemodialysis is thought to offer a better survival advantage to the unborn child. Circulating angiogenic fa...

    Authors: Ayub Akbari, Michelle Hladunewich, Kevin Burns, Felipe Moretti, Rima Abou Arkoub, Pierre Brown and Swapnil Hiremath

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:7

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  28. Content type: Original research article

    Automated peritoneal dialysis (APD) is one of the fastest growing dialysis modalities. It is unknown whether sleep and mood are disturbed while performing repeated overnight exchanges.

    Authors: Maria-Eleni Roumelioti, Christos Argyropoulos, Vernon Shane Pankratz, Manisha Jhamb, Filitsa H. Bender, Daniel J. Buysse, Patrick Strollo and Mark L. Unruh

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:6

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  29. Content type: Reviewer Acknowledgement

    The Editors of Canadian Journal of Kidney Health and Disease would like to thank all our reviewers who have contributed to the journal in Volume 2 (2015).

    Authors: Adeera Levin, Catherine M. Clase, Elizabeth Dicks and Manish M. Sood

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:8

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  30. Content type: Original research article

    Multiple first-morning urine samples are recommended for measuring the urine albumin-to-creatinine ratio (ACR); however, this can be challenging in community-based research.

    Authors: Jessica M. Sontrop, Amit X. Garg, Lihua Li, Kerri Gallo, Virginia Schumann, Jennifer Winick-Ng, William F. Clark and Matthew A. Weir

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:3

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  31. Content type: Original research article

    Hyponatremia is a recognized complication of congestive heart failure (CHF) and is associated with reduced survival. Therefore, early identification and appropriate management of hyponatremia is important. The...

    Authors: Amanda Miller, Bonnie Kuehl, Karthik Tennankore and Steven Soroka

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:4

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  32. Content type: Original research article

    We lack consensus on the clinical value, frequency, and timing of bone mineral density (BMD) testing in kidney transplant recipients. This study sought to determine practice patterns in BMD testing across kidn...

    Authors: Kyla L. Naylor, Guangyong Zou, William D. Leslie, Eric McArthur, Ngan N. Lam, Gregory A. Knoll, S. Joseph Kim, Lisa-Ann Fraser, Jonathan D. Adachi, Anthony B. Hodsman and Amit X. Garg

    Citation: Canadian Journal of Kidney Health and Disease 2016 3:2

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  33. Content type: Original research article

    Achievement of normal volume status is crucial in hemodialysis (HD), since both volume expansion and volume contraction have been associated with adverse outcome and events.

    Authors: Sylvia Kalainy, Ryan Reid, Kailash Jindal, Neesh Pannu and Branko Braam

    Citation: Canadian Journal of Kidney Health and Disease 2015 2:54

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  34. Content type: Original research article

    Predicting the clinical trajectories of chronic kidney disease (CKD) to discern personalized care remains a complex challenge in nephrology. Understanding the appropriate risk thresholds and time frame associa...

    Authors: Helen H. L. Chiu, Navdeep Tangri, Ognjenka Djurdjev, Brendan J. Barrett, Brenda R. Hemmelgarn, François Madore, Claudio Rigatto, Norman Muirhead, Manish M. Sood, Catherine M. Clase and Adeera Levin

    Citation: Canadian Journal of Kidney Health and Disease 2015 2:53

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  35. Content type: Original research article

    Adolescent and young adult kidney transplant recipients have worse graft outcomes than older and younger age groups. Difficulties in the process of transition, defined as the purposeful, planned movement of ad...

    Authors: Rory F. McQuillan, Alene Toulany, Miriam Kaufman and Jeffrey R. Schiff

    Citation: Canadian Journal of Kidney Health and Disease 2015 2:45

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  36. Content type: Original research article

    The rapid increase in glomerular filtration rate in a normal contralateral kidney after uninephrectomy is well known in living kidney donors but much less well described in chronic kidney disease (CKD). The pu...

    Authors: Dominique Dupuis, Georges Ouellet and Louise Roy

    Citation: Canadian Journal of Kidney Health and Disease 2015 2:52

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  37. Content type: Methodology

    Knowledge generation through randomized controlled trials (RCTs) is critical to advance the medical evidence base, inform decision-making, and improve care and outcomes. Unfortunately, nephrology has typically...

    Authors: Claudio Rigatto, Michael Walsh, Nadia Zalunardo, Catherine M Clase, Braden J Manns, François Madore, Susan M Samuel, Catherine J Morgan, Wim Wolfs and Rita S. Suri

    Citation: Canadian Journal of Kidney Health and Disease 2015 2:46

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  38. Content type: Original research article

    Bone marrow-derived early outgrowth cells (EOCs) secrete soluble factors that exert potent renoprotective effects, such that infusion of their conditioned medium recapitulates the affects of the cells themselves.

    Authors: Darren A. Yuen, David M. Kepecs, Yanling Zhang, Suzanne Advani, Kerri Thai, Kim A. Connelly and Richard E. Gilbert

    Citation: Canadian Journal of Kidney Health and Disease 2015 2:44

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  39. Content type: Review

    The Canadian Vasculitis research network (CanVasc) is composed of physicians from different medical specialties, including rheumatology and nephrology and researchers with expertise in vasculitis. One of its a...

    Authors: Lucy McGeoch, Marinka Twilt, Leilani Famorca, Volodko Bakowsky, Lillian Barra, Susan Benseler, David A. Cabral, Simon Carette, Gerald P. Cox, Navjot Dhindsa, Christine Dipchand, Aurore Fifi-Mah, Michele Goulet, Nader Khalidi, Majed M. Khraishi, Patrick Liang…

    Citation: Canadian Journal of Kidney Health and Disease 2015 2:43

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  40. Content type: Review

    Translational research is an evolving discipline that is intended to bridge the gaps between basic science research, clinical research, and implementation in clinical practice. It is a fluid, multidirectional ...

    Authors: Janine F. Farragher, Meghan J. Elliott, Samuel A. Silver, Zsuzsanna Lichner and Anne Tsampalieros

    Citation: Canadian Journal of Kidney Health and Disease 2015 2:42

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  41. Content type: Original research article

    Chronic Kidney Disease (CKD) is a major global health problem. CKD is one of the most common complications of diabetes mellitus and hypertension and carries a risk of cardiovascular morbidity and mortality and...

    Authors: Richard KD Ephraim, Sylvester Biekpe, Samuel A. Sakyi, Prince Adoba, Hope Agbodjakey and Enoch O. Antoh

    Citation: Canadian Journal of Kidney Health and Disease 2015 2:40

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