Table 8 A summary of preventative strategies showing significant reductions in CRBSI
From: Catheter-related bloodstream infection in end-stage kidney disease: a Canadian narrative review
Preventative strategy | Details of impact |
|---|---|
Mupirocin nasal eradication of S. aureus | Reduction in S. aureus bacteremia |
Exit site treatment (mupirocin/polysporinâ„¢) | Reduction in S. aureus and MRSA bacteremia and exit site infection |
Alternate locking solutions | Â |
 46.7 % citrate [65] | Reduction in bacteremia attributable to Staphylococcus spp. Risk of cardiac arrhythmia |
 Taurolidine-citrate [76] | Reduction in risk of bacteremia attributable to Gram-negative spp. |
 Recombinant tPA [66] | Reduction in bacteremia while also significantly reducing catheter failure rate |
Improved catheter hygiene technique [79] (Additional chlorhexidine and 70Â % alcohol at catheter hub/exit at start and end of HD) | Sustained reduction in incident bacteremia and intravenous antibiotic starts during 1-year follow-up |