Skip to main content

Table 3 Multivariable Cox survival analysis for the ESRD-CI and CCI

From: Comorbidity burden at dialysis initiation and mortality: A cohort study

Model

ESRD-CI Group

Events (N)

HR [95 % CI]

Model

CCI Group

Events (N)

HR [95 % CI]

Unadjusted

≤1

2

311

(ref)

1.74 [1.22 to 2.50]

Unadjusted

1

2

311

---

(ref)

 

3

 

1.39 [0.94 to 2.07]

 

3

 

1.84 [1.17 to 2.90]

 

4

 

2.32 [1.62 to 3.32]

 

4

 

1.83 [1.23 to 2.72]

 

5

 

2.37 [1.60 to 3.52]

 

5

 

2.31 [1.54 to 3.47]

 

≥6

 

2.64 [1.91 to 3.65]

 

≥6

 

2.91 [2.04 to 4.15]

Model 1a

≤1

2

311

(ref)

1.60 [1.12 to 2.30]

Model 1a

1

2

311

---

(ref)

 

3

 

1.19 [0.80 to 1.76]

 

3

 

1.64 [1.04 to 2.59]

 

4

 

2.00 [1.40 to 2.86]

 

4

 

1.66 [1.12 to 2.47]

 

5

 

1.97 [1.32 to 2.93]

 

5

 

2.12 [1.41 to 3.18]

 

≥6

 

2.12 [1.52 to 2.93]

 

≥6

 

2.44 [1.71 to 3.49]

Model 2b

≤1

2

311

(ref)

1.62 [1.13 to 2.33]

Model 2b

1

2

311

---

(ref)

 

3

 

1.21 [0.81 to 1.80]

 

3

 

1.66 [1.05 to 2.63]

 

4

 

2.02 [1.41 to 2.90]

 

4

 

1.69 [1.14 to 2.52]

 

5

 

1.99 [1.33 to 2.96]

 

5

 

2.13 [1.42 to 3.21]

 

≥6

 

2.11 [1.52 to 2.93]

 

≥6

 

2.47 [1.73 to 3.53]

Model 3c

≤1

2

311

(ref)

1.60 [1.11 to 2.30]

Model 3c

1

2

311

---

(ref)

 

3

 

1.21 [0.80 to 1.81]

 

3

 

1.64 [1.03 to 2.59]

 

4

 

2.02 [1.40 to 2.93]

 

4

 

1.86 [1.23 to 2.81]

 

5

 

1.91 [1.27 to 2.90]

 

5

 

2.29 [1.48 to 3.54]

 

≥6

 

2.09 [1.49 to 2.93]

 

≥6

 

2.75 [1.86 to 4.08]

Model 4d

≤1

2

311

(ref)

1.57 [1.09 to 2.27]

Model 4d

1

2

311

---

(ref)

 

3

 

1.20 [0.80 to 1.80]

 

3

 

1.63 [1.03 to 2.59]

 

4

 

1.97 [1.36 to 2.87]

 

4

 

1.83 [1.21 to 2.77]

 

5

 

1.86 [1.23 to 2.81]

 

5

 

2.24 [1.44 to 3.47]

 

≥6

 

2.06 [1.46 to 2.89]

 

6

 

2.70 [1.81 to 4.02]

Model 5e

≤1

2

309

(ref)

1.63 [1.12 to 2.36]

Model 5e

1

2

309

---

(ref)

 

3

 

1.28 [0.84 to 1.91]

 

3

 

1.76 [1.10 to 2.82]

 

4

 

1.95 [1.34 to 2.85]

 

4

 

1.86 [1.22 to 2.83]

 

5

 

1.89 [1.25 to 2.86]

 

5

 

2.38 [1.53 to 3.72]

 

≥6

 

1.99 [1.41 to 2.81]

 

≥6

 

2.71 [1.81 to 4.06]

  1. a: Adjusted for age
  2. b: Adjusted for factors in a., race and gender
  3. c: Adjusted for factors in b. and cause of ESRD
  4. d: Adjusted for factors in c. and dialysis type
  5. e: Adjusted for factors in d. and laboratory data (MDRD GFR, albumin, phosphate, hemoglobin)