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Table 3 Multivariable Cox survival analysis for the ESRD-CI and CCI

From: Comorbidity burden at dialysis initiation and mortality: A cohort study

Model ESRD-CI Group Events (N) HR [95 % CI] Model CCI Group Events (N) HR [95 % CI]
Unadjusted ≤1
2
311 (ref)
1.74 [1.22 to 2.50]
Unadjusted 1
2
311 ---
(ref)
  3   1.39 [0.94 to 2.07]   3   1.84 [1.17 to 2.90]
  4   2.32 [1.62 to 3.32]   4   1.83 [1.23 to 2.72]
  5   2.37 [1.60 to 3.52]   5   2.31 [1.54 to 3.47]
  ≥6   2.64 [1.91 to 3.65]   ≥6   2.91 [2.04 to 4.15]
Model 1a ≤1
2
311 (ref)
1.60 [1.12 to 2.30]
Model 1a 1
2
311 ---
(ref)
  3   1.19 [0.80 to 1.76]   3   1.64 [1.04 to 2.59]
  4   2.00 [1.40 to 2.86]   4   1.66 [1.12 to 2.47]
  5   1.97 [1.32 to 2.93]   5   2.12 [1.41 to 3.18]
  ≥6   2.12 [1.52 to 2.93]   ≥6   2.44 [1.71 to 3.49]
Model 2b ≤1
2
311 (ref)
1.62 [1.13 to 2.33]
Model 2b 1
2
311 ---
(ref)
  3   1.21 [0.81 to 1.80]   3   1.66 [1.05 to 2.63]
  4   2.02 [1.41 to 2.90]   4   1.69 [1.14 to 2.52]
  5   1.99 [1.33 to 2.96]   5   2.13 [1.42 to 3.21]
  ≥6   2.11 [1.52 to 2.93]   ≥6   2.47 [1.73 to 3.53]
Model 3c ≤1
2
311 (ref)
1.60 [1.11 to 2.30]
Model 3c 1
2
311 ---
(ref)
  3   1.21 [0.80 to 1.81]   3   1.64 [1.03 to 2.59]
  4   2.02 [1.40 to 2.93]   4   1.86 [1.23 to 2.81]
  5   1.91 [1.27 to 2.90]   5   2.29 [1.48 to 3.54]
  ≥6   2.09 [1.49 to 2.93]   ≥6   2.75 [1.86 to 4.08]
Model 4d ≤1
2
311 (ref)
1.57 [1.09 to 2.27]
Model 4d 1
2
311 ---
(ref)
  3   1.20 [0.80 to 1.80]   3   1.63 [1.03 to 2.59]
  4   1.97 [1.36 to 2.87]   4   1.83 [1.21 to 2.77]
  5   1.86 [1.23 to 2.81]   5   2.24 [1.44 to 3.47]
  ≥6   2.06 [1.46 to 2.89]   6   2.70 [1.81 to 4.02]
Model 5e ≤1
2
309 (ref)
1.63 [1.12 to 2.36]
Model 5e 1
2
309 ---
(ref)
  3   1.28 [0.84 to 1.91]   3   1.76 [1.10 to 2.82]
  4   1.95 [1.34 to 2.85]   4   1.86 [1.22 to 2.83]
  5   1.89 [1.25 to 2.86]   5   2.38 [1.53 to 3.72]
  ≥6   1.99 [1.41 to 2.81]   ≥6   2.71 [1.81 to 4.06]
  1. a: Adjusted for age
  2. b: Adjusted for factors in a., race and gender
  3. c: Adjusted for factors in b. and cause of ESRD
  4. d: Adjusted for factors in c. and dialysis type
  5. e: Adjusted for factors in d. and laboratory data (MDRD GFR, albumin, phosphate, hemoglobin)