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Table 1 Baseline characteristics of patients initiating chronic dialysis in Ontario, Canada from 1998 to 2008

From: The three-year incidence of major hemorrhage among older adults initiating chronic dialysis

   Era, year of dialysis initiation   Patient age, years  
Characteristics Total 1998-2001 2002-2005 2006-2008 p-value 65-74 75-84 ≥85 p-value
  n = 11,173 n = 3,837 n = 4,231 n = 3,105      
Age, mean ± SD 75.8 ± 6.2 74.8 ± 5.8 76.1 ± 6.2 76.5 ± 6.43 <0.001     
Women,% 42.3 42.3 42.0 42.6 0.873 41.6 42.5 44.2 0.286
Race,%          
Caucasian 77.0 70.0 80.7 80.7 <0.001 73.9 79.4 80.5 <0.001
East Asian 6.2 6.6 6.1 5.8   5.9 6.2 7.6  
South Asian 3.0 2.6 3.1 3.5   4.1 2.4 0.7  
Aboriginal 1.1 1.1 1.0 1.2   1.7 0.6 0.4  
Other 4.9 4.4 5.1 5.1   6.2 3.8 3.5  
Unknown 7.9 15.5 4.0 3.6   8.1 7.7 7.4  
Modality,%          
Hemodialysis 81.4 78.5 82.3 80.4 <0.001 77.6 82.8 83.4 <0.001
Peritoneal dialysis 19.5 21.5 17.7 19.6   22.4 17.2 16.6  
Medication*,%          
Clopidogrel 4.5 0.5 5.6 8.0 <0.001 4.3 4.7 4.8 0.571
Warfarin 12.2 11.8 11.9 13.3 0.098 10.6 13.5 13.9 <0.001
Co-morbidity,%          
Atrial fibrillation 14.7 14.0 15.3 14.9 0.258 12.2 16.6 17.8 <0.001
Stroke 5.0 5.8 5.0 4.0 0.003 5.2 4.9 4.5 0.514
Prior Major hemorrhage 10.1 8.9 10.1 11.7 <0.001 10.0 9.8 12.4 0.039
Acute coronary syndrome 13.6 12.7 14.7 13.2 0.026 1.8 2.1 1.8 0.588
Deep vein thrombosis & pulmonary embolism 1.9 1.8 1.8 2.3 0.202 1.8 2.1 1.8 0.588
Mechanical heart valve 1.3 0.9 1.4 1.5 0.022 1.5 1.2 0.3 0.009
Modified Charlson Co-morbidity Indexǂ,%        
2 27.4 27.7 26.7 28.0 <0.001 26.8 27.5 30.2 <0.001
3 13.9 17.5 12.9 10.9   12.2 14.7 18.2  
4 19.0 20.1 17.3 19.9   18.6 19.0 20.9  
≥5 39.7 34.7 43.0 41.2   42.4 38.8 30.6  
  1. *Medication was based on evidence of medication prescription at dialysis initiation.
  2. ǂ We used a modified Charlson Index that gave each individual on dialysis an automatic two-points for moderate-to-severe kidney disease.