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Table 3 Differences in BMD values (g/cm2) and % BMD loss over 1 year between the CHD and NHD groups

From: Conventional hemodialysis is associated with greater bone loss than nocturnal hemodialysis: a retrospective observational study of a convenience cohort

  Baseline (g/cm2) 1 year (g/cm2) % loss (1 year vs baseline) p value BMD after 1 year % greater BMD loss in conventional HD after 1 year (95 % CI)* p valuea
BMD site Conventional Nocturnal Conventional Nocturnal Conventional Nocturnal Conventional Nocturnal   
L-spine 1.13 ± 0.23 0.93 ± 0.12 1.11 ± 0.27 0.92 ± 0.23 2.5 % (1.2–3.8) 1.0 % (0.1–1.9) 0.685 0.819 1.6† (0.2–3.1) 0.02
Total hip 0.84 ± 0.18 0.92 ± 0.15 0.83 ± 0.25 0.91 ± 0.17 2.1 % (1.1–3.1) 1.0 % (0.2–1.8) 0.815 0.792 1.1† (0.1–2.6) 0.03
Femoral neck 0.77 ± 0.15 0.76 ± 0.14 0.76 ± 0.19 0.75 ± 0.19 2.3 % (1.2–3.2) 1.0 % (0.2–1.8) 0.766 0.800 1.3† (0.1–2.5) 0.02
  1. †All values were statistically significantly lower than NHD patients (p < 0.05)
  2. aThis analysis was adjusted for baseline age, weight, dialysis vintage, bone mineral density, and markers of mineral metabolism (predialysis total corrected calcium, phosphate, and parathyroid hormone)