|
Baseline (g/cm2)
|
1 year (g/cm2)
|
% loss (1 year vs baseline)
|
p value BMD after 1 year
|
% greater BMD loss in conventional HD after 1 year (95 % CI)*
|
p valuea
|
---|
BMD site
|
Conventional
|
Nocturnal
|
Conventional
|
Nocturnal
|
Conventional
|
Nocturnal
|
Conventional
|
Nocturnal
| | |
L-spine
|
1.13 ± 0.23
|
0.93 ± 0.12
|
1.11 ± 0.27
|
0.92 ± 0.23
|
2.5 % (1.2–3.8)
|
1.0 % (0.1–1.9)
|
0.685
|
0.819
|
1.6† (0.2–3.1)
|
0.02
|
Total hip
|
0.84 ± 0.18
|
0.92 ± 0.15
|
0.83 ± 0.25
|
0.91 ± 0.17
|
2.1 % (1.1–3.1)
|
1.0 % (0.2–1.8)
|
0.815
|
0.792
|
1.1† (0.1–2.6)
|
0.03
|
Femoral neck
|
0.77 ± 0.15
|
0.76 ± 0.14
|
0.76 ± 0.19
|
0.75 ± 0.19
|
2.3 % (1.2–3.2)
|
1.0 % (0.2–1.8)
|
0.766
|
0.800
|
1.3† (0.1–2.5)
|
0.02
|
- †All values were statistically significantly lower than NHD patients (p < 0.05)
-
aThis analysis was adjusted for baseline age, weight, dialysis vintage, bone mineral density, and markers of mineral metabolism (predialysis total corrected calcium, phosphate, and parathyroid hormone)