Conventional hemodialysis is associated with greater bone loss than nocturnal hemodialysis: a retrospective observational study of a convenience cohort

Table 3 Differences in BMD values (g/cm²) and % BMD loss over 1 year between the CHD and NHD groups

	Baseline (g/cm²)		1 year (g/cm²)		% loss (1 year vs baseline)		p value BMD after 1 year		% greater BMD loss in conventional HD after 1 year (95 % CI)*	p value^a
BMD site	Conventional	Nocturnal	Conventional	Nocturnal	Conventional	Nocturnal	Conventional	Nocturnal
L-spine	1.13 ± 0.23	0.93 ± 0.12	1.11 ± 0.27	0.92 ± 0.23	2.5 % (1.2–3.8)	1.0 % (0.1–1.9)	0.685	0.819	1.6† (0.2–3.1)	0.02
Total hip	0.84 ± 0.18	0.92 ± 0.15	0.83 ± 0.25	0.91 ± 0.17	2.1 % (1.1–3.1)	1.0 % (0.2–1.8)	0.815	0.792	1.1† (0.1–2.6)	0.03
Femoral neck	0.77 ± 0.15	0.76 ± 0.14	0.76 ± 0.19	0.75 ± 0.19	2.3 % (1.2–3.2)	1.0 % (0.2–1.8)	0.766	0.800	1.3† (0.1–2.5)	0.02

†All values were statistically significantly lower than NHD patients (p < 0.05)
^aThis analysis was adjusted for baseline age, weight, dialysis vintage, bone mineral density, and markers of mineral metabolism (predialysis total corrected calcium, phosphate, and parathyroid hormone)

ISSN: 2054-3581