Heparin-anticoagulated acetate-acidified dialysate (n = 15) | Heparin-anticoagulated citrate-acidified dialysate (n = 15) | Regional citrate-anticoagulated dialysis Sessions (n = 15) | p value | |
---|---|---|---|---|
Age (years) | 76 (range 67–90) | 77 (range 55–86) | 84 (range 59–87) | 0.62 |
Sex | 4 male, 5 female | 4 male, 5 female | 5 male, 1 female | 0.3 |
Median dialysis sessions per patient | 1 (range 1–3) | 1 (range 1–3) | 1 (1–5) | |
Gambro Dialyzer 210H | 13 | 13 | 15 | |
Gambro Dialyzer 170H | 2 | 2 | 0 | |
Blood flow (mL/min) | 350 (IQR 305 to 350) | 330 (IQR 310 to 350) | 300 (IQR 300 to 300) | 0.0008 |
Kt/V per session | 1.24 (IQR 1.2 to 1.37) | 1.42 (IQR 1.26 to 1.54) | 1.23 (IQR 1.06 to 1.28) | 0.01 |
Dialysis session duration (minutes) | 240 (range 240 to 270) | 240 (range 240 to 270) | 240 (range 210 to 300) | 1 |
Prescribed net ultrafiltration (L/h dialyzed)a | 0.66 ± 0.21 | 0.71 ± 0.23 | 0.59 ± 0.24 | 0.4 |
Calcium infused (mmol/h dialyzed) | 0 | 0 | 17.2 (range 11.6 to 20) | |
Spent dialysate volume (L) | 124.0 (IQR 122.7 to 125.0) | 124.0 (IQR 122.4 to 124.8) | 131.0 (127 to 148.7) | 0.002 |
Dialysate [Caion] prior to commencement of dialysis in mmol/L | 1.04 (range 1.0 to 1.09) | 0.85 (range 0.83 to 1.05) | <0.00005 | |
Initial dialysate total Ca (mmol/L) | 1.22 ± 0.03 | 1.43 ± 0.07 | 0.01 ± 0.004 | <0.00005 |
Spent dialysate total Ca (mmol/L) | 1.25 ± 0.04 | 1.46 ± 0.05 | 0.55 ± 0.07 | <0.00005 |
Start of session plasma [Caion] (mmol/L) | 1.12 ± 0.09 | 1.12 ± 0.1 | 0.91 | |
End of session plasma [Caion] (mmol/L) | 1.09 ± 0.04 | 1.06 ± 0.04 | 1.06 ± 0.05 | 0.21 |