Atypical antipsychotic medications and hyponatremia in older adults: a population-based cohort study

Table 2 30-day risk of a hospitalization with hyponatremia (as defined by a hospital diagnosis code) in antipsychotic drug users and non-users

	Events, no. (%)^a		Relative risk (95 % CI)	Absolute risk increase (95 % CI), %
	Antipsychotic users	Antipsychotic non-users^b
	(n = 58,008)	(n = 58,008)
Hospitalization with hyponatremia^c	86 (0.15)	53 (0.09)	1.62 (1.15 to 2.29)	0.06 (0.02 to 0.10)

CI confidence interval
^aThe event rates and absolute risk differences are underestimated as the hospital-based diagnosis codes used to define the outcomes have high specificity but low sensitivity
^bAn antipsychotic non-users group was the referent
^cThe sensitivity and specificity of the code for hyponatremia is 11 and 99 %, respectively [30]

ISSN: 2054-3581