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Table 2 30-day risk of a hospitalization with hyponatremia (as defined by a hospital diagnosis code) in antipsychotic drug users and non-users

From: Atypical antipsychotic medications and hyponatremia in older adults: a population-based cohort study

  Events, no. (%)a Relative risk (95 % CI) Absolute risk increase (95 % CI), %
Antipsychotic users Antipsychotic non-usersb
(n = 58,008) (n = 58,008)
 Hospitalization with hyponatremiac 86 (0.15) 53 (0.09) 1.62 (1.15 to 2.29) 0.06 (0.02 to 0.10)
  1. CI confidence interval
  2. aThe event rates and absolute risk differences are underestimated as the hospital-based diagnosis codes used to define the outcomes have high specificity but low sensitivity
  3. bAn antipsychotic non-users group was the referent
  4. cThe sensitivity and specificity of the code for hyponatremia is 11 and 99 %, respectively [30]