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Table 3 Hazard ratios for all-cause mortality in primary and sensitivity analyses

From: Comparative effectiveness of home dialysis therapies: a matched cohort study

Group Number of patients Number of eventsa Deaths per 100 person-years HR (95 % CI)b P value
Main analysis
 Matched sample, intent-to-treat analysis
  PD patients (referent) 2668 868 16.71 1 <0.001
  Daily HD patients 2668 625 12.56 0.75 (0.68–0.82)  
Additional analyses
 Unmatched sample, intent-to-treat analysis, inverse probability of treatment weighting
  PD patients (referent) 74,922 24,638 14.99 1 <0.001
  Daily HD patients 3142 719 12.20 0.84 (0.82–0.86)  
 Matched sample, as-treated analysis (90-day follow-up after modality switches)  
  PD patients (referent) 2668 410 13.33 1 0.005
  Daily HD patients 2668 496 11.52 0.83 (0.74–0.95)  
 Unmatched sample, intent-to-treat analysis, adjusting for propensity score
  PD patients (referent) 74,922 24,638 14.99 1 0.002
  Daily HD patients 3142 719 12.20 0.89 (0.82–0.96)  
 Matched sample, intent-to-treat analysis, index date within 12 months of ESRD date
  PD patients (referent) 877 280 17.04 1 <0.001
  Daily HD patients 877 174 11.03 0.65 (0.54–0.78)  
  1. aFollow-up truncated at 5 years.
  2. bHazard ratio was derived from Cox proportional hazards model including robust variance estimator to account for within-pair correlation