Table 3 Hazard ratios for all-cause mortality in primary and sensitivity analyses
From: Comparative effectiveness of home dialysis therapies: a matched cohort study
| Group | Number of patients | Number of eventsa | Deaths per 100 person-years | HR (95 % CI)b | P value |
|---|---|---|---|---|---|
| Main analysis | |||||
| Matched sample, intent-to-treat analysis | |||||
| PD patients (referent) | 2668 | 868 | 16.71 | 1 | <0.001 |
| Daily HD patients | 2668 | 625 | 12.56 | 0.75 (0.68–0.82) | |
| Additional analyses | |||||
| Unmatched sample, intent-to-treat analysis, inverse probability of treatment weighting | |||||
| PD patients (referent) | 74,922 | 24,638 | 14.99 | 1 | <0.001 |
| Daily HD patients | 3142 | 719 | 12.20 | 0.84 (0.82–0.86) | |
| Matched sample, as-treated analysis (90-day follow-up after modality switches) | |||||
| PD patients (referent) | 2668 | 410 | 13.33 | 1 | 0.005 |
| Daily HD patients | 2668 | 496 | 11.52 | 0.83 (0.74–0.95) | |
| Unmatched sample, intent-to-treat analysis, adjusting for propensity score | |||||
| PD patients (referent) | 74,922 | 24,638 | 14.99 | 1 | 0.002 |
| Daily HD patients | 3142 | 719 | 12.20 | 0.89 (0.82–0.96) | |
| Matched sample, intent-to-treat analysis, index date within 12 months of ESRD date | |||||
| PD patients (referent) | 877 | 280 | 17.04 | 1 | <0.001 |
| Daily HD patients | 877 | 174 | 11.03 | 0.65 (0.54–0.78) | |