|
Serum creatinine
|
Calibration of measure according to IDMS standard
|
|
Optimal measurement using enzymatic assay [15]
|
|
Comparison across laboratories or measurement techniques [16]
|
|
Relevancy of e-alert systems using estimated baseline creatinine
|
|
If previous creatinine available, chosen definition of baseline creatinine
|
|
Management of outliers measures
|
|
Significance of small changes in serum creatinine in patients with low weight/body surface or with pre-existing CKD
|
|
Performance of e-alert system in unselected population of patients.
|
|
Management of multiple alert in a same patient
|
|
Influence of fluid balance/dilution [17].
|
|
Urine output
|
Difference in measurement according to setting (ICU vs. Ward, Specificity of paediatric units, rate of Foley catheter use).
|
|
Management of missing data
|
|
Errors in reading [8]
|
|
Errors related to manual entry of urinary output
|
|
Differences related to measurement (hourly vs. by shift vs. daily)
|
|
Recognition of the lack of specificity of oliguria [18–20]
|
|
Cross-tabulation between serum creatinine and UO
|
