Characteristics
|
All patients (n = 194)
|
Hypovolemic (n = 17)
|
Normovolemic (n = 83)
|
Hypervolemic (n = 94)
|
P value
|
---|
VS, L (assessed by BCM)
|
1.1 ± 2
|
−2.1 ± 0.6
|
0.1 ± 0.7a
|
2.6 ± 1.5b,c
|
<0.001*
|
VS/ECFV% (assessed by BCM)
|
7.8 ± 12
|
−12 ± 3.4
|
0.9 ± 4a
|
17 ± 10b,c
|
<0.001*
|
Clinical target weight
|
72 ± 22
|
85 ± 28
|
74 ± 21
|
69 ± 20c
|
0.014*
|
VS, L (clinically assessed)
|
2.2 ± 2.0
|
2.1 ± 1.3
|
1.7 ± 1.5
|
2.5 ± 2.3b
|
0.016*
|
VS/ECFV (clinically assessed)
|
0.2 + 1.2
|
11.6 ± 8.2
|
10 ± 9
|
16.8 ± 15b
|
0.001*
|
Gender, M/F
|
115/79
|
10/7
|
47/36
|
58/36
|
0.702
|
Age, years
|
61 ± 15
|
60 ± 16
|
60 ± 16
|
62 ± 15
|
0.788
|
Diabetes, %
|
45 %
|
47 %
|
3 %
|
54 %c
|
0.035*
|
Smoking, %
|
11 %
|
0 %
|
6 %
|
17 %c
|
0.02*
|
Edema, %
|
28 %
|
0 %
|
9 %
|
47 %b,c
|
<0.001*
|
Obesity, %
|
26 %
|
47 %
|
30 %
|
19 %b,c
|
0.001*
|
Pre-HD-SBP, mmHg
|
131 ± 25
|
128 ± 26
|
129 ± 26
|
137 ± 25
|
0.088
|
Pre-HD-DBP, mmHg
|
71 ± 16
|
70 ± 15
|
72 ± 18
|
72 ± 16
|
0.843
|
Pre-HD-PP, mmHg
|
60 ± 22
|
59 ± 29 b
|
57 ± 19
|
65 ± 19b
|
0.025*
|
Pre-HD-MAP, mmHg
|
91 ± 17
|
89 ± 14
|
91 ± 19
|
94 ± 17
|
0.418
|
HTN, %
|
45 %
|
41 %
|
36 %
|
54 %c
|
0.015*
|
Antihypertensive
|
48 %
|
24 %
|
45 %
|
54 %
|
0.057
|
Intradialytic hypotension
|
17 %
|
35 %
|
20 %
|
11 %b
|
0.007*
|
Paradoxical hypertension
|
31 %
|
35 %
|
29 %
|
32 %
|
0.840
|
Plasma sodium, mmol/L
|
136 ± 3
|
136 ± 2.6
|
137 ± 3
|
135.5 ± 3c
|
0.002*
|
Serum potassium, mEq/L
|
4.7 ± 0.6
|
4.8 ± 0.6
|
4.6 ± 0.6
|
4.8 ± 0.7
|
0.163
|
Albumin, g/L
|
36 ± 3.5
|
36 ± 4
|
37 ± 3.
|
36 ± 3.5
|
0.184
|
-
VS volume status, VS/ECFV volume status/extracellular fluid volume, pre-HD-SBP pre-hemodialysis systolic blood pressure, pre-HD-DBP pre-hemodialysis diastolic blood pressure, pre-HD-PP pre-hemodialysis pulse pressure, pre-HD-MAP pre-hemodialysis mean arterial pressure, HTN hypertension
- *P < 0.05
-
aSignificant difference between hypovolemic and normovolemic
-
bSignificant difference between hypovolemic and hypervolemic
-
cSignificant difference between normovolemic and hypervolemic