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Table 3 Baseline characteristics of patients stratified by SPPB

From: Frailty and physical function in chronic kidney disease: the CanFIT study

Variable SPPB ≥ 10 (N = 95) SPPB < 10 (N = 122) P-Value
  Age (years) 62.9 (52.9–72.3) 74.6 (63.4–82.5) <0.0001
  Gender (Female) 27 (29.4 %) 57 (48.3 %) 0.0054
  Weight (kg) 81.2 (72–95.9) 86.1 (71.7–96.6) 0.3352
  Systolic Blood Pressure (mmHg) 135 (123–149) 140 (126–151) 0.2047
  Diastolic Blood Pressure (mmHg) 78 (68–85) 71 (65–78) 0.0008
  Pulse Pressure (mmHg) 59 (48–70) 69.5 (57–79) <0.0001
Laboratory Values    
  eGFR (mL/min/1.73 m2) 18 (13–26) 20 (16–27) 0.0901
  Creatinine (umol/L) 273.5 (202–404) 229 (186–309) 0.0273
  Log Urine ACR 3.3 (1.1–5) 3.3 (0.9–5.2) 0.7659
  Hemoglobin (g/L) 118 (110–126) 113 (105–122) 0.0107
  Hemoglobin A1c (%) 5.9 (5.5–7.5) 6.8 (5.8–8.1) 0.0014
  Blood Glucose (mmol/L) 6.2 (5.3–8.5) 7.3 (5.5–9.9) 0.0793
Comorbidities    
  Visual / Hearing Impairment 32 (33.7 %) 69 (56.6 %) 0.0008
  Hypertension 76 (80.0 %) 105 (89.0 %) 0.0682
  Dyslipidemia 55 (57.9 %) 78 (67.2 %) 0.1617
  Diabetes (Type I or II) 40 (42.1 %) 88 (75.2 %) <0.0001
  Previous MI 5 (5.3 %) 24 (20.5 %) 0.0013
  Congestive Heart Failure 5 (5.3 %) 26 (22.2 %) 0.0005
  Neurologic Disease 12 (12.6 %) 39 (33.3 %) 0.0005
  1. Note: Continuous variables are expressed as Median (Interquartile Range) and compared using Mann–Whitney Test; Categorical variables are expressed as N(%) and compared using Chi-Square or Fisher Exact Test
  2. Neurologic Disease = stroke, transient ischemic attack, Parkinson’s disease, ACR Albumin Creatinine Ratio, MI Myocardial Infarction