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Table 3 Baseline characteristics of patients stratified by SPPB

From: Frailty and physical function in chronic kidney disease: the CanFIT study

Variable

SPPB ≥ 10 (N = 95)

SPPB < 10 (N = 122)

P-Value

  Age (years)

62.9 (52.9–72.3)

74.6 (63.4–82.5)

<0.0001

  Gender (Female)

27 (29.4 %)

57 (48.3 %)

0.0054

  Weight (kg)

81.2 (72–95.9)

86.1 (71.7–96.6)

0.3352

  Systolic Blood Pressure (mmHg)

135 (123–149)

140 (126–151)

0.2047

  Diastolic Blood Pressure (mmHg)

78 (68–85)

71 (65–78)

0.0008

  Pulse Pressure (mmHg)

59 (48–70)

69.5 (57–79)

<0.0001

Laboratory Values

   

  eGFR (mL/min/1.73 m2)

18 (13–26)

20 (16–27)

0.0901

  Creatinine (umol/L)

273.5 (202–404)

229 (186–309)

0.0273

  Log Urine ACR

3.3 (1.1–5)

3.3 (0.9–5.2)

0.7659

  Hemoglobin (g/L)

118 (110–126)

113 (105–122)

0.0107

  Hemoglobin A1c (%)

5.9 (5.5–7.5)

6.8 (5.8–8.1)

0.0014

  Blood Glucose (mmol/L)

6.2 (5.3–8.5)

7.3 (5.5–9.9)

0.0793

Comorbidities

   

  Visual / Hearing Impairment

32 (33.7 %)

69 (56.6 %)

0.0008

  Hypertension

76 (80.0 %)

105 (89.0 %)

0.0682

  Dyslipidemia

55 (57.9 %)

78 (67.2 %)

0.1617

  Diabetes (Type I or II)

40 (42.1 %)

88 (75.2 %)

<0.0001

  Previous MI

5 (5.3 %)

24 (20.5 %)

0.0013

  Congestive Heart Failure

5 (5.3 %)

26 (22.2 %)

0.0005

  Neurologic Disease

12 (12.6 %)

39 (33.3 %)

0.0005

  1. Note: Continuous variables are expressed as Median (Interquartile Range) and compared using Mann–Whitney Test; Categorical variables are expressed as N(%) and compared using Chi-Square or Fisher Exact Test
  2. Neurologic Disease = stroke, transient ischemic attack, Parkinson’s disease, ACR Albumin Creatinine Ratio, MI Myocardial Infarction