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Table 3 Associations between participant characteristics and ERI by univariate multinomial logistic regression

From: Association between serum alkaline phosphatase and primary resistance to erythropoiesis stimulating agents in chronic kidney disease: a secondary analysis of the HERO trial

Variable Coefficient 95 % confidence intervals P value
Women (Reference men) −0.83 −2.19 to 0.53 0.2
Non-Caucasians (Reference Caucasians) 0.76 −1.08 to 2.61 0.4
Diabetes mellitus (Reference non-diabetics) 0.85 −0.68 to 2.38 0.3
Cause of kidney disease    
Diabetes Reference   
Glomerulonephritis −1.16 −3.19 to 0.87 0.3
Analgesic nephropathy NR NR NR
Polycystic kidney disease −0.47 −3.46 to 2.52 0.8
Reflux nephropathy −0.47 −3.46 to 2.52 0.8
Renovascular disease NR NR NR
Others −0.29 −1.92 to 1.34 0.7
Smoking status    
Never Reference   
Former 0.47 −0.98 to 1.92 0.5
Current −1.10 −3.54 to 1.35 0.4
Body mass index category    
Healthy weight Reference   
Overweight 1.28 −0.48 to 3.05 0.2
Obese −0.51 −2.20 to 1.18 0.6
Ischemic heart disease −0.28 −1.78 to 1.20 0.7
Congestive heart failure −1.40 −3.26 to 0.46 0.1
Age 0.03 −0.01 to 0.08 0.2
Reticulocyte count −0.01 −0.03 to 0.02 0.5
Total white cell count 0.03 −0.33 to 0.40 0.9
Ferritina 0.01 −0.09 to 0.11 0.8
Transferrin saturationb 0.05 −2.29 to 2.39 0.9
Albumin 0.06 −0.09 to 0.21 0.4
Alkaline phosphatasec 44.01 7.63 to 80.40 0.02
Gamma-glutamyltransferaseb −0.65 −1.60 to 0.30 0.2
Alanine transaminasec −7.42 −16.80 to 1.96 0.1
Aspartate transaminasec −8.50 −20.62 to 3.62 0.2
Lactate dehydrogenaseb −2.18 −5.06 to 0.69 0.1
Albumin-corrected calcium 3.46 −0.60 to 7.51 0.09
Phosphate −0.01 −1.31 to 1.29 0.9
Parathyroid hormonea −0.25 −0.55 to 0.05 0.1
C-reactive protein −0.03 −0.08 to 0.01 0.2
Total F2-isoprostanesb 0.36 −0.69 to 1.42 0.5
Glutathione peroxidise activityd NR NR NR
Superoxide dismutase activitye 1.49 −1.91 to 4.90 0.4
Protein carbonylse 0.24 −1.26 to 1.74 0.8
  1. NR Estimates could not be obtained due to small number of patients
  2. The following non-normally distributed variables were transformed to normality of distribution:
  3. asquare root
  4. blog-transformed
  5. creciprocal of square root
  6. dpower of 3
  7. e reciprocal