Control arm CAC progression rate | Relative risk reduction | Phylloquinone arm progression rate | Sample size per arm for 80% power |
---|---|---|---|
80 | 20% | 64% | 123 |
70 | 20% | 56% | 186 |
60 | 20% | 48% | 270 |
50 | 20% | 40% | 388 |
80 | 25% | 60% | 80 |
70 | 25% | 53% | 121 |
60 | 25% | 45% | 173 |
50 | 25% | 38% | 247 |
RRR = Relative risk reduction |  |  |