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Table 1 Patient serum and urine parameters at presentation and last follow-up

From: PTHrP-related Hypercalcaemia in Infancy and Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)

Serum or urine parameter

At presentation

At last follow-up

Age-appropriate reference interval

Serum creatinine

63 μmol/L

34 μmol/L

<53 μmol/L

Cystatin C eGFR

51 mL/min/1.73 m2

89 mL/min/1.73 m2

>90 mL/min/1.73 m2

Serum calcium

4.98 mmol/L

2.67 mmol/L

2.24-2.74 mmol/L

Serum urea

13.7 mmol/L

6.1 mmol/L

<8.0 mmol/L

Serum bicarbonate

15 mmol/L

21 mmol/L

22-29 mmol/L

Serum sodium

134 mmol/L

139 mmol/L

135-145 mmol/L

Fractional sodium excretion

20.06%

n.d.

N/A

Urine calcium

2.93 mmol/L

1.45 mmol/L

N/A

Uca/cr ratio

9.8 mmol/mmol

0.822 mmol/mmol

<1 at 6 months, <0.6 at 2 years

PTH

0.4 pmol/L

3.3 pmol/L

1.6-6.9 pmol/L

25-vitamin D

140 nmol/L

94 nmol/L

75-225 nmol/L

1,25 dihydroxy-vitamin D

<10 pmol/L

n.d.

39-193 pmol/L

Vitamin A

0.7 μmol/L

n.d.

1.2-2.8 μmol/L

Alkaline phosphatase

206 U/L

296 U/L

<449 U/L

PTHrP

3.8 pmol/L

n.d.

<2 pmol/L

Phosphate

0.83 mmol/L

1.83 mmol/L

1.3-2.6 mmol/L