Skip to main content

Table 5 Multilevel logistic regression examining the association between renin angiotensin system antagonists and acute kidney injury by evidence-based indication (model 1 shows the effects of renin angiotensin system antagonists with no adjustment, model 2 is adjusted for age and gender)

From: Acute kidney injury: an acceptable risk of treatment with renin-angiotensin system blockade in primary care?

Model Interaction p-value Indication Odds ratio (95% CI) P-value
No AKI versus AKI
Model 1 <0.001 No 1.94 (1.72, 2.19) <0.001
   Yes 1.14 (1.04, 1.24) 0.004
Model 2 0.003 No 1.52 (1.34, 1.72) <0.001
   Yes 1.22 (1.12, 1.33) <0.001
No AKI/AKIN1 versus AKIN2/AKIN3
Model 1 <0.001 No 2.31 (1.61, 3.30) <0.001
   Yes 0.98 (0.74, 1.30) 0.90
Model 2 0.005 No 2.04 (1.41, 2.94) <0.001
   Yes 1.05 (0.79, 1.39) 0.73
  1. AKI (acute kidney injury), AKIN1 (acute kidney injury network stage 1), AKIN2 (acute kidney injury network stage 2), AKIN3 (acute kidney injury network stage 3).