Acute kidney injury: an acceptable risk of treatment with renin-angiotensin system blockade in primary care?

Table 4 The association between evidence-based indication, prescription of renin angiotensin system antagonist and acute kidney injury

Indication for ACE/ARB	ACE/ARB	No AKI	AKI
		N (%)	N (%)
No	No	83,724 (97.8%)	1,846 (2.2%)
	Yes	18,331 (96.2%)	721 (3.8%)
Yes	No	25,542 (94.1%)	1,594 (5.9%)
	Yes	72,044 (94.2%)	4,473 (5.8%)
No AKI/AKIN1 versus AKIN2/AKIN3
Indication for ACE/ARB	ACE/ARB	No AKI/AKIN1	AKIN2/AKIN3
		N (%)	N (%)
No	No	85,428 (99.83%)	142 (0.17%)
	Yes	18,989 (99.67%)	63 (0.33%)
Yes	No	27,032 (99.62%)	104 (0.38%)
	Yes	76,267 (99.67%)	250 (0.33%)

AKI (acute kidney injury), AKIN1 (acute kidney injury network stage 1), AKIN2 (acute kidney injury network stage 2), AKIN3 (acute kidney injury network stage 3), CKD (chronic kidney disease), ACE (angiotensin converting enzyme inhibitor), ARB (angiotensin receptor blocker), IHD (ischaemic heart disease), BP (blood pressure).

ISSN: 2054-3581