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Table 4 CKD Prevalence (%) and 95% confidence intervals by age and sex: MDRD vs. CKD-EPI

From: A population-based study of prevalence and risk factors of chronic kidney disease in León, Nicaragua

  Total Males Females
  MDRD* CKD-EPI   MDRD CKD-EPI   MDRD CKD-EPI  
Age N Prevalence (95% CI) N Prevalence (95% CI) P N Prevalence (95% CI) N Prevalence (95% CI) p N Prevalence (95% CI) N Prevalence (95% CI) p
18-29 9 1.6 (0.5, 2.7) 6 1.1 (0.2, 2.0) 0.3§ 8 3.8 (1.2, 6.4) 5 2.4 (0.3, 4.5) 0.3§ 1 0.3 (0.1, 1.7) 1 0.3 (0.1, 1.7) --
30-39 28 3.8 (2.4, 5.2) 22 3 (1.8, 4.2) 0.01 23 6.9 (4.2, 9.6) 19 5.7 (3.2, 8.2) 0.1§ 5 1.3 (0.2, 2.4) 3 0.8 (0.3, 2.2) 0.5§
40-49 40 8.9 (6.3, 11.5) 32 7.1 (4.7, 9.5) 0.005 28 15.4 (10.2, 20.6) 26 14.3 (9.2, 19.4) 0.5§ 12 4.5 (2.0, 7.0) 6 2.2 (0.4, 4.0) 0.01
50-59 68 20.1 (15.8, 24.4) 57 16.8 (12.8, 20.8) 0.0009 46 30.9 (23.5, 38.3) 43 28.9 (21.6, 36.2) 0.3§ 22 11.6 (7.0, 16.2) 14 7.4 (3.7, 11.1) 0.005
60-70 48 29.9 (23.7, 36.1) 53 25.1 (19.2, 31.0) 0.002 26 34.7 (23.9, 45.5) 25 33.3 (22.6, 44) 1.0§ 37 27.2 (19.7, 34.7) 28 20.6 (13.8, 27.4) 0.003
Total 208 9.1 (7.9, 10.3) 170 7.5 (6.4, 8.6) <0.0001 131 13.8 (11.6, 16.0) 118 12.4 (10.3, 14.5) 0.0003 77 5.8 (4.5, 7.1) 52 3.9 (2.9, 4.9) <0.0001
  1. *MDRD: Modification of Diet in Renal Disease equation for estimating glomerular filtration rate.
  2. CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration equation for estimating glomerular filtration rate.
  3. p-value for Mcnemar’s test for paired data.
  4. §Mcnemar’s exact test used for sparse data (i.e. when value for discordant pair MDRD=’yes’ and CKD-EPI=”no” is less than 5).