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Table 5 Secular trends of the proportion of patients who received an anti-thrombotic medication prescription 30 and 120 days preceding a hemorrhagic event

From: The three-year incidence of major hemorrhage among older adults initiating chronic dialysis

Medication Total 1998-2001 2002-2005 2006-2008 P value
Clopidogrel (30 days) 4.2% 1.7% 4.3% 7.0% <0.001
Clopidogrel (120 days) 8.4% 2.6% 9.3% 14.1% <0.001
Warfarin (30 days) 16.6% 17.5% 17.5% 14.3% 0.316
Warfarin (120 days) 29.5% 33.3% 29.2% 25.3% 0.023
Warfarin + Clopidogrel (120 days) 1.8% 0.7% 1.6% 3.4% 0.072