Table 3 Secular trends of the 3-year cumulative incidence (%) and event rates of hemorrhage (per 1000 person years), its subtypes, related endoscopy and all-cause mortality

Total hemorrhage

3-yr incidence

14.43

14.15

14.72

14.36

0.78

Event rate

52.64

51.57

53.87

52.29

Upper gastrointestinal

3-yr incidence

6.06

6.12

5.91

6.18

0.95

Event rate

20.94

21.19

20.41

21.33

Lower gastrointestinal

3-yr incidence

8.88

8.84

9.08

8.66

0.83

Event rate

31.21

31.01

31.97

30.42

Intra-cerebral

3-yr incidence

0.85

0.70

0.90

0.97

0.23

Event rate

2.85

2.35

3.01

3.24

Subarachnoid

3-yr incidence

0.10

0.05

0.14

0.10

0.51

Event rate

0.33

0.17

0.47

0.32

Gastrointestinal endoscopy

3-yr incidence

14.86

15.66

14.06

14.94

0.34

Event rate

54.45

57.76

51.36

54.61