Table 2 Summary of patients’ characteristics at baseline, preoperative and intraoperative measures
All (n = 111) | SCr-, UO-, FOL- (n = 43) | SCr-, UO-, FOL + (n = 32) | SCr-, UO+, FOL- (n = 11) | SCr-, UO+, FOL + (n = 15) | SCr + (n = 10) | P-value | |
|---|---|---|---|---|---|---|---|
Demographics | |||||||
Age (years) | 69 ± 10 | 69 ± 9 | 73 ± 8 | 60 ± 14 | 68 ± 11 | 69 ± 11 | 0.03 |
Male | 84 (76%) | 36 (84%) | 21 (66%) | 9 (82%) | 11 (73%) | 7 (70%) | 0.43 |
Diabetes | 31 (28%) | 10 (23%) | 4 (12%) | 5 (45%) | 6 (40%) | 6 (60%) | 0.01 |
Preoperative Measures | |||||||
Weight (kg) | 80 (68, 91) | 80 (71, 92) | 69 (64, 84) | 84 (78, 111) | 85 (79, 93) | 92 (68, 107) | 0.01 |
Height (cm) | 170 ± 10 | 170 ± 10 | 169 ± 11 | 172 ± 8 | 171 ± 10 | 170 ± 12 | 0.94 |
Creatinine (μmol/L) | 85 (71, 103) | 87 (69, 101) | 80 (71, 93) | 81 (70, 103) | 88 (70, 96) | 117 (90, 144) | 0.01 |
eGFR (mL/min/1.73 m2) | 72 ± 17 | 77 ± 23 | 73 ± 19 | 81 ± 23 | 63 ± 28 | 52 ± 18 | 0.01 |
eGFR <60 mL/min/1.73 m2 | 28 (25%) | 8 (19%) | 7 (23%) | 2 (18%) | 4 (27%) | 7 (70%) | 0.03 |
Recent IV Contrast | 57 (51%) | 15 (35%) | 21 (64%) | 5 (45%) | 9 (60%) | 7 (70%) | 0.05 |
Pre-op ACE/ARB | 73 (66%) | 27 (63%) | 20 (62%) | 9 (82%) | 11 (73%) | 6 (60%) | 0.72 |
Pre-op Diuretics | 31 (28%) | 11 (25%) | 6 (19%) | 3 (27%) | 5 (33%) | 6 (60%) | 0.16 |
Surgery Type | |||||||
MVR Only/AVR Only | 35 (32%) | 12 (28%) | 13 (41%) | 2 (18%) | 4 (27%) | 4 (40%) | 0.17 |
CABG Only | 59 (53%) | 28 (65%) | 13 (41%) | 8 (73%) | 6 (40%) | 4 (40%) | |
CABG + MVR/AVR | 17 (15%) | 3 (7%) | 6 (18%) | 1 (9%) | 5 (33%) | 2 (20%) | |
Intraoperative Measures | |||||||
Duration of Surgery (mins) | 177 (146, 209) | 188 (150, 209) | 156 (122, 190) | 176 (117, 200) | 186 (151, 233) | 200 (173, 243) | 0.007 |
CPB Time (mins) | 92 (72, 108) | 92 (77, 105) | 75 (62, 96) | 84 (46, 100) | 103 (88, 148) | 103 (95, 140) | 0.01 |
Intraoperative pRBC | 24 (22%) | 6 (12%) | 9 (25%) | 1 (0%) | 7 (40%) | 6 (50%) | 0.007 |
Intraoperative Crystalloid (cc) | 1260 (875, 1727) | 1200 (900, 1780) | 1350 (900, 1663) | 850 (700, 1260) | 1050 (845, 1650) | 1386 (1000, 1880) | 0.43 |
Intraoperative Colloid (cc) | 500 (500, 500) | 500 (500, 650) | 500 (500, 600) | 500 (500, 500) | 500 (500, 500) | 500 (500, 500) | 0.54 |
Total Fluid Administered (cc) | 1850 (1485, 2380) | 1820 (1500, 2380) | 1901 (1715, 2398) | 1350 (1100, 1960) | 1730 (1520, 2404) | 2165 (1600, 3412) | 0.08 |
Total Urine Output (cc) | 250 (160, 400) | 325 (175, 500) | 250 (187, 470) | 220 (150, 350) | 260 (125, 400) | 125 (70, 225) | 0.07 |
Total Fluid Balance (cc) | 129 (846, 1700) | 1350 (900, 1720) | 1147 (875, 1519) | 1240 (515, 1825) | 1200 (−686, 1650) | 1765 (105, 2003) | 0.68 |
Negative Fluid Balance at Completion of Surgery | 8 (7%) | 1 (2%) | 0 (0%) | 0 (0%) | 5 (33%) | 2 (20%) | <0.001 |
Postoperative Medications | |||||||
Vasopressors | 85 (77%) | 29 (67%) | 27 (84%) | 6 (54%) | 13 (87%) | 10 (100%) | 0.04 |
Number of Vasopressors | 1 (1, 2) | 1 (0, 1) | 1.5 (1, 2) | 1 (0, 2) | 2 (1, 2) | 2.5 (2, 4) | <0.001 |