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Table 1 Implications to strong and weak/conditional recommendations to different end-users

From: The Canadian Society of Nephrology methods in developing and adapting clinical practice guidelines: a review

End-Users

Strong recommendations

Weak/Conditional recommendations

Patients

Most people in this situation would want the recommended course of action and only a small proportion would not

The majority of people in this situation would want the recommended course of action, but many would not

Clinicians

Most patients should receive the recommended course of action

Be more prepared to help patients to make a decision that is consistent with their own values/decision aids and shared decision making

Policy makers

The recommendation can be adapted as a policy in most situations

There is a need for substantial debate and involvement of stakeholders