Table 2 Significant associations between baseline clinical variables and biomarkers and baseline HRQOL scores, using univariate and multivariate analysis
Characteristic | Reference | Unadjusted B coefficient | 95% C.I. | Adjusted B coefficient | 95% C.I. |
|---|---|---|---|---|---|
SF-36 Physical functioning | |||||
Female | Male | -7.56 | -12.30 to -2.81** | ||
Age | Per 1 year | -0.49 | -0.63 to -0.35** | -0.38 | -0.56 to -0.20** |
Body Mass Index | Per 1 kg/m2 | -0.63 | -1.05 to -0.20** | ||
Diabetes | No Diabetes | -8.25 | -14.27 to -2.23** | ||
Fistula | No Fistula | 12.52 | 6.54 to 18.51** | 10.69 | 3.52 to 17.86** |
Serum Albumin | ≤ 40 g/L | 6.36 | 1.54 to 11.18** | ||
Serum Creatinine | Per 1 umol/L | 0.02 | 0.01 to 0.03** | ||
Sodium | Per 1 mmol/L | 0.76 | 0.06 to 1.46* | ||
White Blood Cells | ≤ 8.1 × 109/L | -7.98 | -13.60 to -2.37** | ||
Neutrophils | ≤ 68% | -7.33 | -12.90 to -1.77** | ||
Leptin | Per 1 ng/ml | -0.17 | -0.26 to -0.08** | ||
Troponin T | ≤ 0.05 ng/ml | -9.54 | -15.60 to -3.48** | ||
NT-proBNP | ≤ 651.9 pg/ml | -6.05 | -12.11 to 0.01* | -6.33 | -12.40 to -0.26* |
IL-6 | Per 1 pg/ml | -0.19 | -0.38 to -0.01* | ||
SF-36 Vitality | |||||
Female | Male | -5.73 | -9.88 to -1.58** | ||
Urea Reduction Ratio | ≤ 60% | 8.58 | 3.52 to 13.64** | 6.33 | 0.48 to 12.17* |
White Blood Cells | ≤ 8.1 × 109/L | -6.76 | -11.62 to -1.91** | ||
Leptin | Per 1 ng/ml | -0.09 | -1.17 to -0.01* | ||
C-reactive protein | Per 1 mg/L | -0.18 | -0.35 to -0.00* | ||
FACIT Fatigue | |||||
Female | Male | -5.00 | -8.26 to -1.73** | ||
Body Mass Index | Per 1 kg/m2 | -0.30 | -0.60 to 0.00* | ||
Diabetes | No Diabetes | -5.07 | -9.40 to -0.73* | ||
Urea Reduction Rate | ≤ 60% | 6.75 | 3.04 to 10.47** | 5.61 | 1.42 to 9.81** |
Leptin | Per 1 ng/ml | -0.10 | -0.17 to -0.04** | ||