Table 2 Univariate analysis of potential risk factors for CVC malfunction

Treatment group

0.02

Heparin-only

1.91 (1.13, 3.22)

rt-PA

Ref.

Age

1.01 (0.99, 1.03)

0.275

Duration of dialysis

0.59 (0.26, 1.38)

0.224

Number of catheters in prior year

1.20 (0.92, 1.57)

0.172

Hemoglobin

1.00 (0.98, 1.02)

0.950

Albumin

1.00 (0.96, 1.04)

0.927

Platelets

1.00 (1.00, 1.00)

0.509

Gender

0.073

Male

Ref.

Female

1.57 (0.95, 2.59)

First dialysis catheter ever

0.878

No

Ref.

Yes

1.04 (0.62, 1.74)

Diabetes

0.352

No

Ref.

Yes

1.27 (0.76, 2.12)

History of rt-PA use for catheter malfunction

0.082

No

Ref.

Yes

1.89 (1.04, 3.46)

CVC reversed at the session prior to the event or censoring:

<0.001

No

Ref.

Yes

11.2 (6.35, 19.7)

> = 1 CVC reversed in the 6 sessions prior to the event or censoring:

<0.001

No

Ref.

Yes

9.50 (4.52, 20.0)

Number of HD sessions with CVC reversed in the 6 sessions prior to the event or censoring

1.71 (1.51, 1.93)

<0.0001

Mean blood processed in the prior 6 runs (L)

 < 65

5.26 (2.00 – 13.87)

<0.001

 65 - 74

3.23 (1.22 – 8.58)

 75 - 84

1.50 (0.51 – 4.41)

 85+

Reference

Mean blood flow in the prior 6 runs (mL/min)

<0.001

 < 300

8.45 (3.20 –22.34)

 300 - 324

6.80 (2.49 – 18.56)

 325 - 349

2.77 (0.90 – 8.49)

 350+

Reference