Skip to main content

Table 2 Univariate analysis of potential risk factors for CVC malfunction

From: Risk factors associated with hemodialysis central venous catheter malfunction; a retrospective analysis of a randomized controlled trial

Variable Hazard ratio (95% CI) P-value
Treatment group   0.02
Heparin-only 1.91 (1.13, 3.22)  
rt-PA Ref.  
Age 1.01 (0.99, 1.03) 0.275
Duration of dialysis 0.59 (0.26, 1.38) 0.224
Number of catheters in prior year 1.20 (0.92, 1.57) 0.172
Hemoglobin 1.00 (0.98, 1.02) 0.950
Albumin 1.00 (0.96, 1.04) 0.927
Platelets 1.00 (1.00, 1.00) 0.509
Gender   0.073
Male Ref.  
Female 1.57 (0.95, 2.59)  
First dialysis catheter ever   0.878
No Ref.  
Yes 1.04 (0.62, 1.74)  
Diabetes   0.352
No Ref.  
Yes 1.27 (0.76, 2.12)  
History of rt-PA use for catheter malfunction   0.082
No Ref.  
Yes 1.89 (1.04, 3.46)  
CVC reversed at the session prior to the event or censoring:   <0.001
No Ref.  
Yes 11.2 (6.35, 19.7)  
> = 1 CVC reversed in the 6 sessions prior to the event or censoring:   <0.001
No Ref.  
Yes 9.50 (4.52, 20.0)  
Number of HD sessions with CVC reversed in the 6 sessions prior to the event or censoring 1.71 (1.51, 1.93) <0.0001
Mean blood processed in the prior 6 runs (L)
 < 65
5.26 (2.00 – 13.87) <0.001
 65 - 74 3.23 (1.22 – 8.58)
 75 - 84 1.50 (0.51 – 4.41)
 85+ Reference
Mean blood flow in the prior 6 runs (mL/min)   <0.001
 < 300 8.45 (3.20 –22.34)  
 300 - 324 6.80 (2.49 – 18.56)
 325 - 349 2.77 (0.90 – 8.49)
 350+ Reference