Skip to main content

Table 1 Characteristics of the study cohort stratified by sex and age categories

From: Mortality risk for women on chronic hemodialysis differs by age

Characteristic Age < 45 Age 45-75 Age > 75
  Women Men P value Women Men P value Women Men P value
N % 39.5(1406) 60.5(2152)   40.0(7044) 60.0(10585)   42.9(3342) 57.1(4442)  
Age (±SD) 35.5 ± 7.4 35.9 ± 7.2 0.1 63.4 ± 8.2 62.9 ± 8.3 <0.0001 81.0 ± 4.0 80.9 ± 4.0 0.5
Race    <0.0001    <0.0001    0.02
Caucasian 57.6(810) 65.1(1400)   70(4856) 74(7490)   77.8(2599) 80.6(3579)  
Aboriginal 15.9(223) 10.3(222)   7.3(644) 4.8(635)   1.6(53) 1.1(51)  
East Asian 6.8(95) 5.3(115)   5.1(359) 6.6(541)   7.8(260) 6.2(275)  
Black 6.1(86) 5.4(116)   3.4(724) 2.8(1234)   9.2(306) 8.9(397)  
South Asian 9.2(129) 9.3(201)   11.1(255) 9.1(345)   1.7(57) 1.3(58)  
Other 4.5(63) 4.6(98)   3.1(206) 2.7(340)   2.0(67) 1.8(82)  
BMI (±SD) 27.2 ± 8.6 26.9 ± 6.5 0.2 28.9 ± 8.1 27.9 ± 6.4 <0.0001 25.8 ± 6.1 25.4 ± 5.3 <0.0001
Distance to nearest dialysis facility in km (IQR) 11.4(5.0-62.2) 11.7(4.8-62.4) 0.7 12.0(4.9-59.5) 12.0(5.0-55.5) 0.9 8.6(4.0-28.8) 9.4(4.4-34.8) 0.06
Any pre-dialysis care % (N) 53.2(748) 50.9(1096) 0.2 58.5(4122) 58.7(6212) 0.8 57.2(1911) 59.2(2630) 0.07
Median number of days with pre-dialysis care (IQR) 562(220–1532) 574(211–1339) 0.9 133 (0–747) 140(0–812) 0.03 587 (217–1218) 666(246–1362) 0.003
Geographic region % (N)    0.08    0.06    0.2
Atlantic 9.2(129) 9.4(202)   11.6(815) 10.8(1137)   10.3(342) 10.4(461)  
Central 19.3(685) 31.6(1122)   51.6(3626) 53.2(5618)   59.2(1969) 57.7(2558)  
Prairie 12(425) 15.9(566)   24.3(1705) 23.2(2447)   17.6(586) 19.5(863)  
Pacific 11.8(166) 12.0(258)   12.5(882) 12.9(1367)   13(431) 12.5(555)  
Co-morbidities: % (N)          
CAD 5.1(72) 5.6(120) 0.6 22.3(1572) 23.7(2508) 0.04 26.4(881) 29.1(1292) 0.008
AMI 3.4(48) 3.8(82) 0.6 19.4(1370) 25.2(2666) <0.0001 22.9(765) 30.3(1344) <0.0001
Pulmonary edema 14.4(202) 11.6(249) 0.02 29.5(2080) 26.8(2837) <0.0001 32(1070) 30.5(1357) 0.2
DM 35.2(495) 36(774) 0.7 56.6(3984) 55.1(5932) 0.06 38.3(1279) 36.1(1602) 0.05
Stroke 3.8(54) 3.3(70) 0.4 14.0(988) 14.6(1541) 0.3 16.7(557) 19.5(865) 0.002
PVD 6.7(94) 6.7(144) 0.9 17.9(1263) 22.4(2370) <0.0001 17.7(590) 23.8(1055) <0.0001
Malignancy 3.4(48) 1.8(38) 0.002 10.7(757) 11.5(1217) 0.2 15(500) 21.5(957) <0.0001
Lung disease 3.4(48) 2.3(49) 0.05 12.7(894) 11.5(1215) 0.02 12.1(405) 15.4(683) <0.0001
HTN 71.3(1003) 77.6(1670) <0.0001 83.3(5870) 83.2(8803) 0.8 84.4(2819) 82(3642) 0.006
Serious illness 9.7(136) 8.5(183) 0.3 11.3(794) 11.3(1198) 0.9 9.4(314) 9.8(437) 0.5
Current smoker 18.5(260) 22.6(487) 0.003 13.4(943) 15.8(1675) <0.0001 5.3(176) 7(313) 0.001
CABG 2.6(36) 1.9(41) 0.2 10.6(748) 16.9(1794) <0.0001 12.3(412) 20.5(909) <0.0001
Number of co-morbidities (±SD) 1.8 ± 1.4 1.8 ± 1.3 0.4 3.0 ± 1.9 3.2 ± 1.9 <0.0001 2.9 ± 1.8 3.3 ± (1.9 <0.0001
Cause of ESRD % (N)    0.02    <0.0001    <0.0001
Vascular 6.9(97) 9.3(200)   17.2(1214) 18.3(1938)   39.3(1312) 39.3(1744)  
DM 31.1(437) 31.4(676)   45.8(3227) 44.3(4694)   26.8(897) 25(1111)  
GN 33.6(472) 31.9(687)   12.2(859) 13.7(1449)   8.7(291) 8.8(389)  
Obstruction 4.6(64) 3.9(83)   2.2(153) 3.0(314)   2.4(81) 4.0(179)  
Interstitial 1.6(22) 0.6(13)   1.3(94) 0.7(74)   1.6(53) 0.9(38)  
PCKD 5.8(82) 5.3(114)   4.6(323) 4.2(445)   1.8(61) 1.6(73)  
Other 7.8(109) 8.2(177)   8.6(607) 7.9(841)   6.5(217) 6.3(279)  
Unknown 8.7(123) 9.4(202)   8.0(567) 7.8(830)   12.9(430) 14.2(629)  
Serum Albumin g/L (±SD) 30.1 ± 10.5 31.5 ± 10.3 <0.0001 31.1 ± 9.5 31.8 ± 9.3 <0.0001 32.2 ± 8.8 32.2 ± 7.1 0.8
Hemoglobin g/L (±SD) 93.9 ± 26.7 97.1 ± 23.9 <0.0001 99.5 ± 32.2 100.3 ± 21.1 0.03 102.0 ± 25.3 102.7 ± 23.9 0.2
AVF/AVG % (N) 11.6(163) 17.3(372) <0.0001 16.6(1168) 20.6(2181) <0.0001 14.5(483) 18.9(838) <0.0001
  1. N number, % percentage, SD standard deviation, BMI body mass index, IQR interquartile range, km kilometer, Atlantic include Newfoundland, New Brunswick, Nova Scotia, prince Edward Island, Central Ontario, Prairie Manitoba, Saskatchewan, Alberta, Pacific British Columbia. CAD coronary artery disease, AMI acute myocardial infarction, DM diabetes mellitus, HTN hypertension, CABG coronary artery bypass graft, ESRD end stage renal disease, g/L grams per litre, Any pre-dialysis was defined as contact with a Nephrologist 30 days prior to renal replacement therapy initiation, AVF/AVG arteriovenous fistula/arteriovenous graft.