Table 1 Univariate analysis. Baseline characteristics/demographics

ESA exposure (%)

4 (3)

128 (97)

–

–

<0.0001

NODAT Yes (%)

–

–

4 (8)

48 (92)

–

Age at transplant (years)

58.2 ± 11.6

50.7 ± 13.4

0.0001

51.8 ± 13.8

51.4 ± 13.2

0.51

Male (%)

33 (63)

248 (62)

0.89

68 (51)

213 (67)

0.002

Donor source deceased (%)

33 (63)

187 (47)

0.005

78/ (60)

142 (45)

0.005

Body mass index (BMI)

26.9 ± 6.5

26.2 ± 5

0.43

25.8 ± 4.9

26.5 ± 5.3

0.21

Hepatitis C+ yes (%)

0 (0)

4 (1)

0.76

1 (0.7)

3(0.9)

0.63

Acute rejection (AR) yes (%)

2 (4)

26 (6)

0.35

11 (8)

17(5)

0.22

Cause end-stage renal disease:

 Hypertension

11

33

0.003

11

33

0.51

 Glomerulonephritis

25

196

0.88

70

151

0.27

 Polycystic kidney disease

6

55

0.65

16

45

0.57

 Interstitial nephritis

2

46

0.06

14

34

0.98

 Obstructive uropathy

1

6

0.57

1

6

0.34

 Other

7

63

0.66

20

50

0.88

Blood glucose at start of ESA (N = 13/N = 129)

7.3 ± 2

6.2 ± 1.4

0.04

–

–

–

Blood glucose at the end of ESA (N = 13/N = 129)

5.3 ± 1.5

5.7 ± 1.2

0.08

–

–

–

Tacrolimus IR yes (%)

40 (77)

311 (78)

0.86

104 (79)

247 (77)

0.75

Cyclosporine yes (%)

9 (17)

55 (14)

0.49

11 (8)

53 (16)

0.02

Tacrolimus ER (Advagraf) yes (%)

8 (15)

74 (18.5)

0.67

20 (15)

61 (19)

0.31

Prednisone yes (%)

50 (96)

345 (86)

0.02

121 (92)

274 (86)

0.09

Creatinine (SCr) at initial hospital discharge (umol/L)

162.8 ± 110.2

180.4 ± 147.7

0.32

225.1 ± 188.3

157.5 ± 113

0.0002

 SCr at 3 months (umol/L)

114.3 ± 35.2

127.2 ± 43.6

0.05

136.4 ± 56.5

121.1 ± 34.4

0.005

 SCr at 6 months (umol/L)

119.3 ± 36.7

128.9 ± 49.8

0.10

142.9 ± 70.3

121.1 ± 32.6

0.001

Hemoglobin (Hb) at discharge

98 ± 17.8

98.7 ± 14.9

0.76

93.8 ± 14.8

100.8 ± 15

<.0001

 Hb at 3 months

120.8 ± 16.8

123 ± 17.2

0.41

117.7 ± 16.2

125 ± 16.9

<.0001

 Hb at 6 months

131.6 ± 14.4

128.5 ± 18.2

0.25

123.4 ± 17.3

131.3 ± 17.5

<.0001

Random blood glucose (RBG) at discharge

7.1 ± 2.1

5.8 ± 1.7

<.0001

6 ± 1.8

6 ± 1.8

0.93

 RBG at 3 months

7.7 ± 2.3

5.9 ± 1.3

<.0001

6.2 ± 1.6

6.1 ± 1.7

0.65

 RBG at 6 months

6.9 ± 1.6

5.6 ± 0.9

<.0001

5.5 ± 1

5.8 ± 1.2

0.01