Association between serum alkaline phosphatase and primary resistance to erythropoiesis stimulating agents in chronic kidney disease: a secondary analysis of the HERO trial

Table 2 Associations between participant characteristics and ERI by simple linear regression

Variable	R²	P value
Women (Reference men)	−0.02	0.8
Non-Caucasians (Reference Caucasians)	−0.02	0.7
Diabetes mellitus (Reference non-diabetics)	0.01	0.2
Cause of kidney disease	−0.03	0.6
Smoking status	−0.02	0.6
Body mass index	0.02	0.2
Ischemic heart disease	−0.01	0.4
Congestive heart failure	0.02	0.2
Age	0.01	0.2
Reticulocyte count	−0.01	0.6
Total white cell count	−0.02	0.8
Ferritin^a	−0.01	0.5
Transferrin saturation^b	−0.01	0.6
Albumin	0.001	0.3
Alkaline phosphatase^c	0.06	0.03
Gamma-glutamyltransferase^b	0.01	0.2
Alanine transaminase^c	0.02	0.1
Aspartate transaminase^c	0.04	0.09
Lactate dehydrogenase^b	0.07	0.05
Albumin-corrected calcium	0.05	0.06
Phosphate	−0.02	0.9
Parathyroid hormone^a	0.04	0.09
C-reactive protein	0.03	0.09
Total F2-isoprostanes^b	−0.01	0.5
Glutathione peroxidise activity^d	−0.004	0.9
Superoxide dismutase activity^e	−0.01	0.5
Protein carbonyls^e	−0.03	0.9

The following non-normally distributed variables were transformed to normality of distribution:
^asquare root
^blog-transformed
^creciprocal of square root
^dpower of 3
^ereciprocal

ISSN: 2054-3581